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“Creating a Hope”: a mixed-method approach to identify most acceptable evidence-based psycho-social intervention to improve the retention in care among Indian youth diagnosed with multi-drug resistant TB (MDR-TB)

PI: Gauri Dhumal, Johns Hopkins, BJ Government Medical College, Pune, India
Project Dates: February 2022 - March 2024
 
The aim of the project is to assess the psycho-social barriers to retention in care among youth with MDR-TB and identify the most acceptable evidence based psycho-social intervention among Indian youth with Multi-Drug Resistant TB. The project objectives are to (1) identify the barriers to retention in care by a qualitative inquiry; (2)  identify evidence based effective psycho-social interventions for youths through literature research and (3) assess the acceptability of proposed youth friendly psycho-social interventions. This will be a mixed method study design which includes quantitative semi-structured interviews and qualitative in-depth interviews. The expected outcomes of the project will be to identify the barriers faced by the youth and  the most acceptable and preferred youth friendly evidence based intervention. The study will be conducted at BJ. Government Medical College-Clinical Research Site, Pune, India. 

Project updates

As of August 2023, the PI reports that the team completed the qualitative data collection and analysis along with the quantitative data collection for the research project.   79 quantitative interviews have been conducted to date. Data entry and analysis of other quantitative interviews are in process. This cross-sectional study adopted a mixed-method approach for data collection. The team conducted six in-depth interviews and 30 semi-structured interviews  with adolescents and young adults (AYA) with MDR-TB between April 2022 to March 2023 registered at public MDR-TB hospital. Qualitative data employed thematic analysis using MAXQDA-Pro-2022 software and STATA was utilized for quantitative analysis. 
 
The mixed method data was used to write an abstract titled, “Creating-A-Hope: Most preferred psycho-social intervention among Adolescents and young adults with Multidrug-Resistant Tuberculosis to improve programmatic outcomes in Pune, India”, which was submitted in and accepted to be presented  at the Union World Conference on Lung Health  to be held  November 15 -19, 2023 in Paris. 

In terms of mentorship activities, there are three mentees involved in this project. Two of them have learned about the research procedures in terms of Institutional Review Board (IRB) requirement for the research, data collection tool designing, data collection procedure and data entry. Data cleaning and analysis procedure learning is ongoing. One mentee has been enrolled for the PhD. She is learning manuscript writing and is one of the co-authors in the abstract submitted through this study for the international conference. 
 
 
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