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Recent Publications

(Including joint publications with other units)  

BioSecurity ChallengesBiosecurity Challenges of the Global Expansion of High Containment Biological Laboratories (December 2011)
During July 10-13, 2011, 68 participants from 32 countries gathered in Istanbul, Turkey for a workshop organized by the United States National Research Council on Anticipating Biosecurity Challenges of the Global Expansion of High containment Biological Laboratories. The United States Department of State's Biosecurity Engagement Program sponsored the workshop, which was held in partnership with the Turkish Academy of Sciences. The international workshop examined biosafety and biosecurity issues related to the design, construction, maintenance, and operation of high-containment biological laboratories- equivalent to United States Centers for Disease Control and Prevention biological safety level 3 or 4 labs. Although these laboratories are needed to characterize highly dangerous human and animal pathogens, assist in disease surveillance, and produce vaccines, they are complex systems with inherent risks. Biosecurity Challenges of the Global Expansion of High-Containment Biological Laboratories summarizes the workshop discussion, which included the following topics:
  • Technological options to meet diagnostic, research, and other goals;
  • Laboratory construction and commissioning;
  • Operational maintenance to provide sustainable capabilities, safety, and security; and
  • Measures for encouraging a culture of responsible conduct.
Workshop attendees described the history and current challenges they face in their individual laboratories. Speakers recounted steps they were taking to improve safety and security, from running training programs to implementing a variety of personnel reliability measures. Many also spoke about physical security, access controls, and monitoring pathogen inventories. Workshop participants also identified tensions in the field and suggested possible areas for action. Committee on International Security and Arms Control (CISAC) 
 
 
A View of Global Science A View of Global Science and technology: Letter Report (December 2011)
This letter report describes the 2009-2011 activities of the Board on Global Science and Technology (BGST) and provides an initial characterization of the global S&T landscape that the Board can use as a roadmap to develop future activities. BGST met five times between November 2009 and May 2011. Board meetings were devoted to (1) identifying national security implications of the globalization of S&T, (2) building a baseline understanding of current indicators for the U.S. posture with regard to the evolving global S&T landscape, and (3) developing a BGST engagement strategy. The letter portion of the report summarizes activities of the board in its first year, and also describes some existing approaches to identifying and/or benchmarking emerging technologies globally. It is followed by 5 appendixes which include three experimental examples of a qualitative approach to benchmarking, and brief descriptions of programs that are part of the National Academies complex, with which BGST has cooperated. (Board on Global Science and Technology)  
 
  
There are few areas of human endeavor in which the challenge of sustainability is clearer than in food and agriculture. Farmers and animal keepers must use natural resources the physical environment of soil, water, and the sun in ways that generate a continuous supply of food adequate to satisfy people's biological needs for survival and their economic demands. Degradation of soil, inappropriate management of water, and the use of practices that have negative effects on the climate may increase food security in the short run, but will decrease output over time and threaten the survival of future generations. Sustainable management of natural resources and the environment is fundamental to future food security. Action by governments and other agents within and outside the food system may help or hinder sustainability. There is much evidence showing that the current global food system is not sustainable.Measuring Food Insecurity and Assessing the Sustainability of Global Food Systems summarizes the National Research Council's workshop, held in May 2011, which explored ways to assure sustainable food availability, identifying (a) the major barriers to expanding food production to meet future food demand without damaging future productive capacity and (b) policy, technology, and governance interventions that could reduce these barriers and promote sustainable food availability as a basic pillar of sustainable food security. The workshop was organized around the three broad dimensions of sustainable food security: availability, access, and utilization. Within these topics, the workshop aimed to review the existing data to encourage action and identify the knowledge gaps. (Science and Technology for Sustainability (STS))  

 Growing Innovation Clusters for American Prosperity: Summary of a Symposium (October 2011)
Responding to the challenges of fostering regional growth and employment in an increasingly competitive global economy, many U.S. states and regions have developed programs to attract and grow companies as well as attract the talent and resources necessary to develop innovation clusters. These state and regionally based initiatives have a broad range of goals and increasingly include significant resources, often with a sectoral focus and often in partnership with foundations and universities. These are being joined by recent initiatives to coordinate and concentrate investments from a variety of federal agencies that provide significant resources to develop regional centers of innovation, business incubators, and other strategies to encourage entrepreneurship and high-tech development. This has led to renewed interest in understanding the nature of innovation clusters and public policies associated with successful cluster development. The Board on Science, Technology, and Economic Policy (STEP), conducted a symposium which brought together state and federal government officials, leading analysts, congressional staff, and other stakeholders to explore the role of clusters in promoting economic growth, the government's role in stimulating clusters, and the role of universities and foundations in their development. Growing Innovation Clusters for American Prosperity captures the presentations and discussions of the 2009 STEP symposium on innovation clusters. It includes an overview highlighting key issues raised at the meeting and a summary of the meeting's presentations. This report has been prepared by the workshop rapporteur as a factual summary of what occurred at the workshop. (Board on Science, Technology, and Economic Policy (STEP))

Examining Core Elements of International Research Collaboration: Summary of a Workshop (September 2011) 
The globalization of science, engineering, and medical research is proceeding rapidly. The globalization of research has important implications for the U.S. research enterprise, for the U.S. government agencies, academic institutions, and companies that support and perform research, and for the world at large. As science and technology capabilities grow around the world, U.S.-based organizations are finding that international collaborations and partnerships provide unique opportunities to enhance research and training. At the same time, significant obstacles exist to smooth collaboration across national borders. Enhancing international collaboration requires recognition of differences in culture, legitimate national security needs, and critical needs in education and training. (Government University Industry Research Round Table (GUIRR))

Increasing Resilience Increasing National Resilience to Hazards and Disasters: The Perspective from the Gulf Coast of Louisiana and Mississippi:
Summary of a Workshop
 (September 2011)
Natural disasters are having an increasing effect on the lives of people in the United States and throughout the world. Every decade, property damage caused by natural disasters and hazards doubles or triples in the United States. More than half of the U.S. population lives within 50 miles of a coast, and all Americans are at risk from such hazards as fires, earthquakes, floods, and wind. The year 2010 saw 950 natural catastrophes around the world--the second highest annual total ever--with overall losses estimated at $130 billion. The increasing impact of natural disasters and hazards points to increasing importance of resilience, the ability to prepare and plan for, absorb, recover from, or more successfully adapt to actual or potential adverse events, at the individual , local, state, national, and global levels. Increasing National Resilience to Hazards and Disasters reviews the effects of Hurricane Katrina and other natural and human-induced disasters on the Gulf Coast of Louisiana and Mississippi and to learn more about the resilience of those areas to future disasters. Topics explored in the workshop range from insurance, building codes, and critical infrastructure to private-sector issues, public health, nongovernmental organizations and governance. This workshop summary provides a rich foundation of information to help increase the nation's resilience through actionable recommendations and guidance on the best approaches to reduce adverse impacts from hazards and disasters. (Committee on Science, Engineering, and Public Policy (COSEPUP)/Earth and Life Studies (DELS)

Designing the Microbial Research Commons: Proceedings of an International Worksh

Designing the Microbial Research Commons: Proceedings of an International Workshop (September 2011)
Recent decades have witnessed an ever-increasing range and volume of digital data. All elements of the pillars of science--whether observation, experiment, or theory and modeling--are being transformed by the continuous cycle of generation, dissemination, and use of factual information. This is even more so in terms of the re-using and re-purposing of digital scientific data beyond the original intent of the data collectors, often with dramatic results. We all know about the potential benefits and impacts of digital data, but we are also aware of the barriers, the challenges in maximizing the access, and use of such data. There is thus a need to think about how a data infrastructure can enhance capabilities for finding, using, and integrating information to accelerate discovery and innovation. How can we best implement an accessible, interoperable digital environment so that the data can be repeatedly used by a wide variety of users in different settings and with different applications? With this objective: to use the microbial communities and microbial data, literature, and the research materials themselves as a test case, the Board on Research Data and Information held an International Symposium on Designing the Microbial Research Commons at the National Academy of Sciences in Washington, DC on 8-9 October 2009. The symposium addressed topics such as models to lower the transaction costs and support access to and use of microbiological materials and digital resources from the perspective of publicly funded research, public-private interactions, and developing country concerns. The overall goal of the symposium was to stimulate more research and implementation of improved legal and institutional models for publicly funded research in microbiology. (Board on Research Data and Information (BRDI))

Reference Manual on ScienceReference Manual on Scientific Evidence: Third Edition (September 2011)
The Reference Manual on Scientific Evidence, Third Edition, assists judges in managing cases involving complex scientific and technical evidence by describing the basic tenets of key scientific fields from which legal evidence is typically derived and by providing examples of cases in which that evidence has been used. First published in 1994 by the Federal Judicial Center, the Reference Manual on Scientific Evidence has been relied upon in the legal and academic communities and is often cited by various courts and others. Judges faced with disputes over the admissibility of scientific and technical evidence refer to the manual to help them better understand and evaluate the relevance, reliability and usefulness of the evidence being proffered. The manual is not intended to tell judges what is good science and what is not. Instead, it serves to help judges identify issues on which experts are likely to differ and to guide the inquiry of the court in seeking an informed resolution of the conflict. The core of the manual consists of a series of chapters (reference guides) on various scientific topics, each authored by an expert in that field. The topics have been chosen by an oversight committee because of their complexity and frequency in litigation. Each chapter is intended to provide a general overview of the topic in lay terms, identifying issues that will be useful to judges and others in the legal profession. They are written for a non-technical audience and are not intended as exhaustive presentations of the topic. Rather, the chapters seek to provide judges with the basic information in an area of science, to allow them to have an informed conversation with the experts and attorneys. (Committee on Science, Technology, and Law (CSTL))

Building the 21st Century: U.S. China Cooperation on Science, Technology, and InBuilding the 21st Century: U.S. China Cooperation on Science, Technology, and Innovations (August 2011)
The global economy is characterized by increasing locational competition to attract the resources necessary to develop leading-edge technologies as drivers of regional and national growth. One means of facilitating such growth and improving national competitiveness is to improve the operation of the national innovation system. This involves national technology development and innovation programs designed to support research on new technologies, enhance the commercial return on national research, and facilitate the production of globally competitive products. Understanding the policies that other nations are pursuing to become more innovative and to what effect is essential to understanding how the nature and terms of economic competition are shifting. Building the 21st Century U.S.-China Cooperation on Science, Technology, and Innovation studies selected foreign innovation programs and comparing them with major U.S. programs. This analysis of Comparative Innovation Policy includes a review of the goals, concept, structure, operation, funding levels, and evaluation of foreign programs designed to advance the innovation capacity of national economies and enhance their international competitiveness. This analysis focuses on key areas of future growth, such as renewable energy, among others, to generate case-specific recommendations where appropriate.(Board on Science, Technology and Economic Policy (STEP)

Sustainability and the U.S. EPA

Sustainability and the U.S. EPA (August 2011)
Sustainability is based on a simple and long-recognized factual premise: Everything that humans require for their survival and well-being depends, directly or indirectly, on the natural environment. The environment provides the air we breathe, the water we drink, and the food we eat. Recognizing the importance of sustainability to its work, the U.S. Environmental Protection Agency (EPA) has been working to create programs and applications in a variety of areas to better incorporate sustainability into decision-making at the agency. To further strengthen the scientific basis for sustainability as it applies to human health and environmental protection, the EPA asked the National Research Council (NRC) to provide a framework for incorporating sustainability into the EPA's principles and decision-making. This framework, Sustainability and the U.S. EPA, provides recommendations for a sustainability approach that both incorporates and goes beyond an approach based on assessing and managing the risks posed by pollutants that has largely shaped environmental policy since the 1980s. Although risk-based methods have led to many successes and remain important tools, the report concludes that they are not adequate to address many of the complex problems that put current and future generations at risk, such as depletion of natural resources, climate change, and loss of biodiversity. Moreover, sophisticated tools are increasingly available to address cross-cutting, complex, and challenging issues that go beyond risk management. The report recommends that EPA formally adopt as its sustainability paradigm the widely used "three pillars" approach, which means considering the environmental, social, and economic impacts of an action or decision. Health should be expressly included in the "social" pillar. EPA should also articulate its vision for sustainability and develop a set of sustainability principles that would underlie all agency policies and programs.(Science and Technology for Sustainability (STS))

Research-Doc in Biomed

Research-Doctorate Programs in the Biomedical Sciences: Selected Findings from the NRC Assessment (July 2011)
Research Doctorate Programs in the Biomedical Sciences: Selected Findings from the NRC Assessment examines data on the biomedical sciences programs to gather additional insight about the talent, training environment, outcomes, diversity, and international participation in the biomedical sciences workforce. This report supports an earlier publication, A Data-Based Assessment of Research-Doctorate Programs in the United States, which analyzes data and rankings from more than 5,000 doctoral programs, 982 of which were in the biomedical sciences. Research Doctorate Programs in the Biomedical Sciences explores questions about degrees and completion rates as they relate to GRE scores, student funding, program facilities, diversity among faculty members, and other variables. The report examines 11 biomedical science fields including cell and developmental biology, genetics and genomics, microbiology, nutrition, and physiology, among others. (Board on Higher Education and Workforce  (BHEW))

Expanding Underrepresented Minority Participation: America's Science and Technol

Expanding Underrepresented Minority Participation: America's Science and Technology
Talent at the Crossroads
 (June 2011)
In order for the United States to maintain the global leadership and competitiveness in science and technology that are critical to achieving national goals, we must invest in research, encourage innovation, and grow a strong and talented science and technology workforce. Expanding Underrepresented Minority Participation explores the role of diversity in the science, technology, engineering and mathematics (STEM) workforce and its value in keeping America innovative and competitive. According to the book, the U.S. labor market is projected to grow faster in science and engineering than in any other sector in the coming years, making minority participation in STEM education at all levels a national priority. Expanding Underrepresented Minority Participation analyzes the rate of change and the challenges the nation currently faces in developing a strong and diverse workforce. Although minorities are the fastest growing segment of the population, they are underrepresented in the fields of science and engineering. Historically, there has been a strong connection between increasing educational attainment in the United States and the growth in and global leadership of the economy. Expanding Underrepresented Minority Participation suggests that the federal government, industry, and post-secondary institutions work collaboratively with K-12 schools and school systems to increase minority access to and demand for post-secondary STEM education and technical training. The book also identifies best practices and offers a comprehensive road map for increasing involvement of underrepresented minorities and improving the quality of their education. It offers recommendations that focus on academic and social support, institutional roles, teacher preparation, affordability and program development. (Committee on Science, Engineering, and Public Policy (COSEPUP) )

Pathways to Urban SustainabilityPathways to Urban Sustainability: Lessons from the Atlanta Metropolitan Region: Summary of a Workshop (June 2011)
In order for the United States to maintain the global leadership and competitiveness in science and technology that are critical to achieving national goals, we must invest in research, encourage innovation, and grow a strong and talented science and technology workforce. Expanding Underrepresented Minority Participation explores the role of diversity in the science, technology, engineering and mathematics (STEM) workforce and its value in keeping America innovative and competitive. According to the book, the U.S. labor market is projected to grow faster in science and engineering than in any other sector in the coming years, making minority participation in STEM education at all levels a national priority. Expanding Underrepresented Minority Participation analyzes the rate of change and the challenges the nation currently faces in developing a strong and diverse workforce. Although minorities are the fastest growing segment of the population, they are underrepresented in the fields of science and engineering. Historically, there has been a strong connection between increasing educational attainment in the United States and the growth in and global leadership of the economy. Expanding Underrepresented Minority Participation suggests that the federal government, industry, and post-secondary institutions work collaboratively with K-12 schools and school systems to increase minority access to and demand for post-secondary STEM education and technical training. The book also identifies best practices and offers a comprehensive road map for increasing involvement of underrepresented minorities and improving the quality of their education. It offers recommendations that focus on academic and social support, institutional roles, teacher preparation, affordability and program development.(Science and Technology for Sustainability (STS))

Review of the Scientific Approaches Used During the FBI's Investigation of the Anthrax Letters (May 2011)
Less than a month after the September 11, 2001 attacks, letters containing spores of anthrax bacteria (Bacillus anthracis, or B. anthracis) were sent through the U.S. mail. Between October 4 and November 20, 2001, 22 individuals developed anthrax; 5 of the cases were fatal. During its investigation of the anthrax mailings, the FBI worked with other federal agencies to coordinate and conduct scientific analyses of the anthrax letter spore powders, environmental samples, clinical samples, and samples collected from laboratories that might have been the source of the letter-associated spores. The agency relied on external experts, including some who had previously developed tests to differentiate among strains of B. anthracis. In 2008, seven years into the investigation, the FBI asked the National Research Council (NRC) of the National Academy of Sciences (NAS) to conduct an independent review of the scientific approaches used during the investigation of the 2001 B. anthracis mailings. Committee on Science, Technology and Law (CSTL)/Board on Life Sciences
 

Research Training 2011Research Training in the Biomedical, Behavioral, and Clinical Research Sciences (February 2011)
Comprehensive research and a highly-trained workforce are essential for the improvement of health and health care both nationally and internationally. During the past 40 years the National Research Services Award (NRSA) Program has played a large role in training the workforce responsible for dramatic advances in the understanding of various diseases and new insights that have led to more effective and targeted therapies. In spite of this program, the difficulty obtaining jobs after the postdoc period has discouraged many domestic students from pursuing graduate postdoc training. In the United States, more than 50 percent of the postdoc workforce is made up of individuals who obtained their Ph.D.s from other countries. Indeed, one can make a strong argument that the influx of highly trained and creative foreigners has contributed greatly to U.S. science over the past 70 years. Research Training in the Biomedical, Behavioral, and Clinical Research Sciences discusses a number of important issues, including: the job prospects for postdocs completing their training; questions about the continued supply of international postdocs in an increasingly competitive world; the need for equal, excellent training for all graduate students who receive NIH funding; and the need to increase the diversity of trainees. The book recommends improvements in minority recruiting, more rigorous and extensive training in the responsible conduct of research and ethics, increased emphasis on career development, more attention to outcomes, and the requirement for incorporating more quantitative thinking in the biomedical curriculum. (Board on Higher Education and Workforce  (BHEW))

Book Cover

Certifiably Sustainable?: The Role of Third-Party Certification Systems: Report of a Workshop (July 2010)
Consumption of goods and services represents a growing share of economic activity globally. In the United States, consumption accounts for more than two-thirds of gross domestic product. This trend of increasing consumption has brought with it negative consequences for the environment and human well-being. Global demand for energy, food, and all manner of goods is on the rise, putting strains on the natural and human capital required to produce them. Extractive industries and production processes are prominent causes of species endangerment. Modern economies are underpinned by substantial energy consumption, a primary contributor to the current climate crisis. Expanding international trade has led to many economic opportunities, but has also contributed to unfair labor practices and wealth disparities. In order to take a step in learning from this field of practice, the National Academies' Science and Technology for Sustainability Program held a workshop to illuminate the decision making process of those who purchase and produce certified goods and services. It was also intended to help clarify the scope and limitations of the scientific knowledge that might contribute to the economic success of certified products. The workshop, summarized in this volume, involved presentations and discussions with approximately 40 invited experts from academia, business, government, and nongovernmental organizations. (Science and Technology for Sustainability (STS))

cover image Gender Differences at Critical Transitions in the Careers of Science, Engineering, and Mathematics Faculty(June 2010)
This report presents new and surprising findings about career differences between female and male full-time, tenure-track, and tenured faculty in science, engineering, and mathematics at the nation's top research universities. Much of this congressionally mandated book is based on two unique surveys of faculty and departments at major U.S. research universities in six fields: biology, chemistry, civil engineering, electrical engineering, mathematics, and physics. A departmental survey collected information on departmental policies, recent tenure and promotion cases, and recent hires in almost 500 departments. A faculty survey gathered information from a stratified, random sample of about 1,800 faculty on demographic characteristics, employment experiences, the allocation of institutional resources such as laboratory space, professional activities, and scholarly productivity. This book paints a timely picture of the status of female faculty at top universities, clarifies whether male and female faculty have similar opportunities to advance and succeed in academia, challenges some commonly held views, and poses several questions still in need of answers. This book will be of special interest to university administrators and faculty, graduate students, policy makers, professional and academic societies, federal funding agencies, and others concerned with the vitality of the U.S. research base and economy. (Committee on Women in Science, Engineering, and Medicine (CWSEM)) 

Steps Toward Large-Scale Data Integration in the Sciences: Summary of a Workshop(June 2010)
In August 2009 the National Research Council held a workshop to identify some of the major challenges that hinder large-scale data integration in the sciences and some of the technologies that could lead to solutions. The workshop examined a collection of scientific research domains, with application experts explaining the issues in their disciplines and current best practices. This approach allowed the participants to gain insights about both commonalities and differences in the data integration challenges facing the various communities. The workshop also featured experts working on the cutting edge of techniques for handling data integration problems. Workshop participants identified areas in which the emerging needs of research communities are not being addressed and opportunities for addressing these needs through closer engagement between the affected communities and cutting-edge computer science. (Policy and Global Affairs (PGA) /Board on Mathematical Sciences and their Applications)


cover imageExpanding Biofuel Production: Sustainability and the Transition to Advanced Biofuels: Summary of a Workshop (April 2010)
While energy prices, energy security, and climate change are front and center in the national media, these issues are often framed to the exclusion of the broader issue of sustainability--ensuring that the production and use of biofuels do not compromise the needs of future generations by recognizing the need to protect life-support systems, promote economic growth, and improve societal welfare. Thus, it is important to understand the effects of biofuel production and use on water quality and quantity, soils, wildlife habitat and biodiversity, greenhouse gas emissions, air quality, public health, and the economic viability of rural communities. (Science and Technology for Sustainability (STS) Policy and Global Affairs (PGA)

 

Letter Report for the Committee on Deterring Cyberattacks: Informing Strategies and Developing Options for U.S. Policy  (March 2010)
This report is the first phase of a larger project to conduct a broad, multidisciplinary examination of deterrence strategies and their possible utility to the U.S. government in its policies toward preventing cyberattacks. This first phase identifies the key issues and questions that merit examination. The next phase will engage experts to prepare papers that address key issues and questions, including those posed here. The report provides basic information needed to understand the nature of the problem and to articulate important questions that can drive research regarding ways of more effectively preventing, discouraging, and inhibiting hostile activity against important U.S. information systems and networks. (Policy and Global Affairs (PGA) /Computer Science and Telecommunications Board)

The return of the once-dormant economies of China and India to dynamism and growth is one of the most remarkable stories in recent history. The two countries are home to nearly 40 percent of the world's population, but until recently neither had played an influential role in the contemporary global economy. In the past two decades, China and India have liberalized internal economic policy, treatment of foreign investment, and trade, and have experienced economic growth at sustained high rates. From the point of view of the United States, however, the most important development in the Chinese and Indian economies in the long term may be the strides they are making in developing their own domestic innovation capacities. After a long period of underinvestment, both countries have committed to growing their science and education systems to bolster research and further economic expansion. (Board on Science, Technology and Economic Policy (STEP))
   

 

 

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